Biomimetic poly(glycerol sebacate)/poly(l-lactic acid) blend scaffolds for adipose tissue engineering

Poly(lactic acid) (PLA) Nanofibers for Bone Tissue Engineering

Collagen-hyaluronic acid scaffolds for adipose tissue engineering.

Three-dimensional (3-D) in vitro models of the mammary gland require a scaffold matrix that supports the development of adipose stroma within a robust freely permeable matrix. 3-D porous collagen-hyaluronic acid (HA: 7.5% and 15%) scaffolds were produced by controlled freeze-drying technique and crosslinking with 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride. All scaffolds displa...

Biomimetic Calcium Phosphate-Polycarbonate Composite Scaffolds for Bone Tissue Engineering

Shuang S Chen and Joachim Kohn New Jersey Center for Biomaterials, Rutgers The State University of New Jersey, Piscataway, New Jersey 08854, United States. Statement of Purpose: Large bone defects resulting from trauma, tumor resection, congenital abnormalities or reconstructive surgery are challenging clinical problems that are usually treated with autografts and allografts. However, donor sit...

Biomimetic poly(lactide) based fibrous scaffolds for ligament tissue engineering.

The aim of this study was to fabricate a fibrous scaffold that closely resembled the micro-structural architecture and mechanical properties of collagen fibres found in the anterior cruciate ligament (ACL). To achieve this aim, fibrous scaffolds were made by electrospinning L-lactide based polymers. L-Lactide was chosen primarily due to its demonstrated biocompatibility, biodegradability and hi...

Fibers of Poly (lactic-co-glycolic Acid) / Poly (isoprene) Blend for Application in Tissue Engineering

Tissue engineering can be easily described as the in vitro seeding and attachment of human cells onto a scaffold in order to develop new tissue. The application of polymers as scaffolds may bring interesting properties, such as bioresorbability, biocompatibility, mechanical behavior closer to that presented by the original tissue. Poly (Lactic-coGlycolic Acid) (PLGA) and Poly(Isoprene) (PI) wer...